Reply to Uludag: fMRI "initial dip" reflects increase in oxygenated hemoglobin

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

To dip or not to dip: reconciling optical imaging and fMRI data.

Several optical studies have reported a brief initial increase of deoxyhemoglobin (1), which is consistent with an initial dip observed in the functional MRI (fMRI) signal, evoked by local neuronal activity. This effect is small and not always present (2), but it has stirred great interest because it may reflect a rapid increase of oxidative metabolism before increases in blood flow and, thus, ...

متن کامل

Initial increase in blood CD4(+) lymphocytes after HIV antiretroviral therapy reflects redistribution from lymphoid tissues.

Previous studies proposed a dynamic, steady-state relationship between HIV-mediated cell killing and T-cell proliferation, whereby highly active antiretroviral therapy (HAART) blocks viral replication and tips the balance toward CD4(+) cell repopulation. In this report, we have analyzed blood and lymph node tissues obtained concurrently from HIV-infected patients before and after initiation of ...

متن کامل

Hemorphin 7 reflects hemoglobin proteolysis in abdominal aortic aneurysm.

OBJECTIVE In human abdominal aortic aneurysm, the accumulation of blood-derived cells and proteases within the mural thrombus plays a pivotal role in the evolution toward vessel wall rupture. We sought to identify peptides released from abdominal aortic aneurysm specimens, characterized by an intraluminal thrombus. METHODS AND RESULTS Intraluminal thrombus samples were analyzed by differentia...

متن کامل

Glycation of fetal hemoglobin reflects hyperglycemia exposure in utero.

OBJECTIVE The lifetime risk of metabolic diseases in offspring of women with gestational diabetes mellitus (GDM) depends, at least in part, on the impact of glycemic fetal programming. To quantify this impact, we have developed and validated a unique mass spectrometry method to measure the percentage of glycated hemoglobin in cord blood. RESEARCH DESIGN AND METHODS This case-control study inc...

متن کامل

A mathematical model relating cortical oxygenated and deoxygenated hemoglobin flows and volumes to neural activity.

OBJECTIVE To describe a toolkit of components for mathematical models of the relationship between cortical neural activity and space-resolved and time-resolved flows and volumes of oxygenated and deoxygenated hemoglobin motivated by optical intrinsic signal imaging (OISI). APPROACH Both blood flow and blood volume and both oxygenated and deoxygenated hemoglobin and their interconversion are a...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Proceedings of the National Academy of Sciences

سال: 2010

ISSN: 0027-8424,1091-6490

DOI: 10.1073/pnas.0915004107